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Aromasin 25mg Tablets

Buy Aromasin 25mg Tablets Online - Generic Exemastane

Generic Exemastane Tablets - Aromasin 25mg Tablets

Availability: In stock

$4.59
Quantity Strenth Unit Price Price Cart
30 Tablets Aromasin 25mg Tablets - Generic Exemestane $4.95 $148.35
90 Tablets Aromasin 25mg Tablets - Generic Exemestane $4.46 $401.35

Brief description of Aromasin:

Aromasin decreases the estrogen levels in postmenopausal women that decline the growth of certain types of breast tumors which requires estrogen to grow in the body. Aromasin is used to treat breast cancer in postmenopausal women. It is most commonly given to women whose cancer has progressed even after surgery, radiation, or other cancer medications have been tried without success.

How do Aromasin works?

Breast cancer cell growth may be estrogen-dependent. Aromasin with an active ingredient Exemestane is the principal enzyme that converts androgens to estrogens both in pre- and postmenopausal women. While the main source of estrogen (primarily estradiol) is the ovary in premenopausal women, the principal source of circulating estrogens in postmenopausal women is from the conversion of adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) by the aromatase enzyme in peripheral tissues. Estrogen deprivation through aromatase inhibition is an effective and selective treatment for some postmenopausal patients with hormone-dependent breast cancer. Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition". Exemestane significantly lowers circulating estrogen concentrations in postmenopausal women but has no detectable effect on the adrenal biosynthesis of corticosteroids or aldosterone. This reduction in serum and tumor concentrations of estrogen delays tumor growth and disease progression. Exemestane has no effect on other enzymes involved in the steroidogenic pathway up to a concentration at least 600 times higher than that inhibiting the aromatase enzyme.

Dosage Information for Aromasin:

Aromasin is available in 25mg strength. The recommended dose of Aromasin in early and advanced breast cancer is 25mg tablet to be taken once a day, particularly after meals. You must consult the doctor before using this medication. In patients with early breast cancer, treatment with Aromasin should continue until completion of 5 years of combined sequential adjuvant hormonal therapy and patients with advanced breast cancer, treatment should continue until the tumor progression is evident.  

Missed Dose: In case the dose is missed, you should take the missed dose as soon as possible. Try not to miss the dose.

Overdose: In the case of overdose, seek medical attention as soon as possible.

There are some side effects likely to occur while using Aromasin such as cough or hoarseness, difficulty in breathing, fever or chills, lower back or side pains, mental depression, swelling in hands and legs, tightness in chest, weight gain and yellow skin.

Contraindications:

  • Not to be administered to women with pre-menopausal endocrine status
  • Should be used with caution in patients with renal or hepatic impairment
  • Aromasin contains fructose, so it should not be given to patients with fructose intolerance
  • Contraindicated in patients with hypersensitivity to the active ingredient Exemestane

Drug Interactions:

Co-medications that induce CYP 3A4 (e.g., Rifampicin, Phenytoin, Carbamazepine, Phenobarbital, or St. John's wort) may significantly decrease exposure to Exemestane.

Storage Conditions:

Keep Aromasin at room temperature away from heat, sunlight, and moisture. Keep it out of reach from children and pets.

Precautionary measures:

There are some precautionary measures to be kept in mind while using Aromasin such as-

  • Avoid using the medication during pregnancy and breast feeding
  • Do not intake alcohol or tobacco products while using Aromasin
  • The effect of medication won't work if it is taken along with hormone medication or birth control pills. 

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